The Big Bang Theory, season premiere at 8pm on CBS

– Leonard (Johnny Galecki) may still be at sea at the start of the season but it won’t be long before he’s back on dry land with Penny (Kaley Cuoco). A reunion that won’t happen as quickly? One with roommate Sheldon (Jim Parsons), who will be shocked when he leans that Leonard secretly retuned from the Stephen Hawking expedition and chose to spend his first days with Penny. Also look for Amy (Mayim Bialik) and Bernadette (Melissa Rauch) to take their fist Penny-less road trip together.

Parks & Recreation, 1-hour season premiere at 8pm on NBC

– Though Leslie (Amy Poehler) is facing a recall, the season 6 premiere sends her and the gang to London where she will receive a women-in-government award. Meanwhile, Andy (Chris Pratt) stays in London to work on a charity project, and Chris (Rob Lowe) and Anne (Rashida Jones) will continue to date and baby-make before exiting the show in episode 13. Also, Orphan Black’s Tatiana Maslany guests in two episodes as a permit-seeking doctor who catches the eye of Tom (Aziz Ansari). His way to win her heart: bureaucratic incompetence. He purposefully screws up her permit request to keep her around as long as possible.

The Crazy Ones, series premiere at 9pm on CBS

– Academy Award winner Robin Williams returns to television in The Crazy Ones, a single-camera workplace comedy about a larger-than-life advertising genius whose unorthodox methods and unpredictable behavior would get him fired… if he weren’t the boss. Simon Roberts is the head of a powerful agency, with the biggest clients and brands in the world, but even more important to him is having his daughter Sydney (Sarah Michelle Gellar) by his side. As his partner, Sydney is Simon’s exact opposite – focused, organized and eager to make a name for herself, but also too busy parenting her father, which she’d resent if he wasn’t so brilliant at what he does. Joining them in the firm are the dashing and talented Zach; art director Andrew, who’s as hard-working as he is neurotic; and the beautiful and deceptively smart assistant Lauren. With his team and his daughter behind him, Simon continues to set the advertising world on fire, and it looks like they are definitely buying what these crazy ones are selling.

Glee, season premiere at 9pm on FOX

When news broke of star Cory Monteith’s death this summer, fans couldn’t imagine how the show could go on. But it will, with a tribute episode planned for Oct. 10, which will deal with the passing of Monteith’s beloved Finn. But first, Glee will kick off its fifth season with an elaborate Beatles tribute, including Blaine (Darren Criss) wooing Kurt (Chris Colfer) with a marching-band-led “Got to Get You Into My Life.”

Grey’s Anatomy, 2-hour season premiere at 9pm on ABC

– While the massive storm continues outside Grey Sloan Memorial in the 2-hour season 10 premiere, inside the drama barrels on right where we left off in the finale. Richard (James Pickens Jr.) remains in mortal danger after being electrocuted, Meredith (Ellen Pompeo) and Derek (Patrick Dempsey) will have to juggle two kids, and Callie (Sara Ramirez) and Arizona (Jessica Capshaw) will see fallout after their marriage is rocked by Arizona’s infidelity. As for the newly split up Owen (Kevin McKidd) and Cristina (Sandra Oh), executive producer Shonda Rhimes teases “we see the show starting to take Cristina and Owen to a new place.”

The Michael J. Fox Show, 1-hour series premiere at 9pm on NBC

– Look who’s making the news again! One of NY’s most beloved news anchors, Mike Henry (Michael J. Fox, Spin City, Family Ties), put his career on hold to spend more time with his family and focus on his health after he was diagnosed with Parkinson’s. But now five years later, with the kids busy growing up and Mike growing restless, it just might be time for him to get back to work. Having never wanted Mike to leave in the first place, his old boss Harris Green (Wendell Pierce, Treme, The Wire) jumped at the chance to get him back on TV. The trick, as it’s always been, was to make Mike think it was his idea. After several – okay, many – failed attempts, Mike’s family, anxious to see him out of the house, finally succeeded in getting him to “run into” Green. Now their plan is in motion. He’ll be back to juggling home, family and career, just like the old days – only better.

Two and a Half Men, season premiere at 9:30pm on CBS

– The boys’ club is breaking up: With Angus T. Jones off to college and not expected to return to the show anytime soon, Amber Tamblyn is moving into the beach house for the hit comedy’s 11th season, playing Charlie Harper’s long-lost lesbian daughter. Who, as it turns out, is exactly like her father. “She’s a fun, hard-partying girl who loves everything her father did—including women,” says showrunner Jim Patterson. With Alan (Jon Cryer) and Walden (Ashton Kutcher) both single, expect awkward double dates and conflicts with their new roomie.

Parenthood, season premiere at 10pm on NBC

– With Kristina (Monica Potter) cancer-free, Crosby (Dax Shepard) and Jasmine (Joy Bryant) expecting, and Sarah (Lauren Graham) once again single, fans were bracing themselves for the fact that May’s neatly-tied-up season 4 finale would be their last visit with the Bravermans. One 22-episode pickup later, executive producer Jason Katims has plenty of time to delve back into the drama, including Julia (Erika Christensen) and Joel’s (Sam Jaeger) troubled marriage and Kristina’s political ambitions. But as far as Sarah’s personal life, Graham believes her character should stay single and get lots of action for a woman in her 40s.

Elementary, season premiere at 10pm on CBS

Elementary stars Jonny Lee Miller as detective Sherlock Holmes and Lucy Liu as Dr. Joan Watson in a modern-day drama about a crime-solving duo that cracks the NYPD’s most impossible cases. Hopefully we’ll see Moriarty, who was revealed to be Irene Adler, resurface at some point in season 2—if Game of Thrones actress Natalie Dormer’s schedule permits. But two other names from the Sherlock canon will definitely show up in the premiere when Watson accompanies Holmes to London to help his struggling former colleague Inspector Lestrade (Sean Pertwee) – and ends up meeting Mycroft Holmes (Rhys Ifans), the smart, successful estranged brother Sherlock looks down on. Good news for Rhys I-fans: Mycroft will eventually make his way to New York for an extended arc.

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