Medium, season premiere at 8pm on CBS

– The supernatural drama series is inspired by the real-life story of medium Allison Dubois (Patricia Arquette), an extraordinary young wife and mother who, since childhood, has struggled to make sense of her dreams and visions of dead people. Dubois works as a consultant to District Attorney Manuel Devalos, using her psychic abilities to solve violent and horrifying crimes that baffle Phoenix police and others within the criminal justice system. Assisting her crime-solving endeavors is Detective Lee Scanlon, her longtime ally in the local police department. Meanwhile, at home, Dubois’ husband Joe, an aerospace engineer, is a supportive husband and father who is also busy launching his own scientific engineering company. Their daughters, Ariel, Bridgette and Marie all seem to have inherited their mother’s abilities to varying, expanding degrees. Entering it’s seventh season, the Dubois family will experience a lot of big changes as Ariel leaves home for Dartmouth, which prompts Allison to finish her own long-delayed law degree. This life change will bring Allison into contact with lots of new and interesting people, which will cause tension with Joe. Also this season, Scanlon’s recently deceased brother will wreak ghostly havoc on Allison.

Smallville, season premiere at 8pm on The CW

– The end of the beginning starts here. Taking flight in its tenth and final season, this modern retelling of a Superman’s legendary origins continues to blend realism, action, heart and humor as Clark Kent (Tom Welling) soars toward claiming his birthright. We can look forward to a whole slew of favorite guest stars from past seasons coming back. Also this season, one huge Lois and Clark moment in the first eight episodes and a fulfilling wrap-up for Chloe. Exec producer Brian Peterson says the final chapter will find Clark facing the ghosts of his past so he can become the hero he’s destined to be.

The Good Guys, season premiere at 9pm on FOX

– It’s the ultimate guilty pleasure show, having aired it’s first season over the summer I was actually kinda sad when there were no more new episodes to air. Well, my guilty pleasure is back and I’m rejoicing! From Matt Nix, the creator of Burn Notice, comes this action comedy about a pair of extremely mismatched detectives who expose the big picture of small crime. Dan Stark (Bradley Whitford) used to be a big-shot detective in his glory days in the 70s. A stranger to modern police work who would much rather trust his old-school police instincts, Dan has the reputation as being a bit of a wild card able to skate by on the heroic deeds of his yesteryear. Jack Bailey (Colin Hanks) is Dan’s new partner. He’s been given the thankless task of babysitting Dan, the drunk pariah who can never keep partners for long. Jack may not see it, but he has little chance of getting out of his situation; his knack for making enemies at the station has assured he is not going anywhere. The show is very one-dimensional and there is zero depth to these characters, but it also a very enjoyable and easy-going.

CSI: NY, season premiere at 9pm on CBS

– It’s CSI but in New York, so that means the cases are completely different, right? Melina Kanakaredes, who plays Stella, has left the show and replacing her is Jo Danville (Sela Ward), a confident, professional Southern woman who enjoys family time and whose work is driven by her empathy for the victim. As for the season six cliffhanger when serial killer Shane shot at Danny, (SPOILER ALERT) well no one on the team has died.

Supernatural, season premiere at 9pm on The CW

– Returning for its sixth season, this haunting series follows Sam and Dean Winchester, two brothers bound by tragedy and blood to their dangerous, other-worldly mission. This past season, Dean and Sam faced their toughest foe yet: the Devil himself. As the Apocalypse raged on around them, the brothers, aided only by a dwindling band of fellow hunters and rebel angel Castiel, sought a way to stop Lucifer and save the planet. Ultimately, they discovered a way to force Lucifer back into Hell and end the Apocalypse-but at tremendous cost: Sam’s life. Season 6 picks up one year after they averted the Apocalypse and there’s a big shocker in store: Sam is very much alive. What kind of monsters are they trying to kill this season? Exec producer Sera Gamble says they will be tackling vampires, werewolves, leprechauns and fairies. “All of those things that were on your Trapper Keeper in the third grade.”

Blue Bloods, season premiere at 10pm on CBS

– This new crime drama follows a multi-generational family of cops dedicated to New York City law enforcement. Frank Reagan (Tom Selleck) is the New York City Police Commissioner. He runs his department as diplomatically as he runs his family, even when dealing with the politics that plagued his unapologetically bold father, Henry, during his stint as Chief. A source of pride and concern for Frank is his eldest son Danny, a seasoned detective, family man, and Iraqi War vet who on occasion uses dubious tactics to solve cases. The sole Reagan woman in the family, Erin, is a N.Y. Assistant D.A. and newly single parent, who also serves as the legal compass for her siblings and father. Jamie is the youngest Reagan, fresh out of Harvard Law and the family’s “golden boy;” however, unable to deny the family tradition, Jamie decided to give up a lucrative future in law and is now a newly minted cop. Jamie’s life takes an abrupt turn when he’s asked to become part of a clandestine police investigation even his father knows nothing about, and one that could impact the family’s legacy. With Selleck as the leading man, it’s one of EW’s Top 5 Picks for new shows this season.

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